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Aurora A activation in mitosis promoted by BuGZ

Protein phase separation or coacervation has emerged as a potential mechanism to regulate biological functions. We have shown that coacervation of a mostly unstructured protein, BuGZ, promotes assembly of spindle and its matrix. BuGZ in the spindle matrix binds and concentrates tubulin to promote mi...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Huang, Yuejia, Li, Teng, Ems-McClung, Stephanie C., Walczak, Claire E., Prigent, Claude, Zhu, Xueliang, Zhang, Xuemin, Zheng, Yixian
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748987/
https://ncbi.nlm.nih.gov/pubmed/29074706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201706103
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