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Aurora A activation in mitosis promoted by BuGZ
Protein phase separation or coacervation has emerged as a potential mechanism to regulate biological functions. We have shown that coacervation of a mostly unstructured protein, BuGZ, promotes assembly of spindle and its matrix. BuGZ in the spindle matrix binds and concentrates tubulin to promote mi...
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| Publicat a: | J Cell Biol |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5748987/ https://ncbi.nlm.nih.gov/pubmed/29074706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201706103 |
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