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Spindle assembly checkpoint signaling and sister chromatid cohesion are disrupted by HPV E6-mediated transformation

Aneuploidy, a condition that results from unequal partitioning of chromosomes during mitosis, is a hallmark of many cancers, including those caused by human papillomaviruses (HPVs). E6 and E7 are the primary transforming proteins in HPV that drive tumor progression. In this study, we stably expresse...

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Pubblicato in:Mol Biol Cell
Autori principali: Shirnekhi, Hazheen K., Kelley, Erin P., DeLuca, Jennifer G., Herman, Jacob A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509418/
https://ncbi.nlm.nih.gov/pubmed/28539402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-12-0853
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