Measuring the effects of ketamine on mGluR5 using [(18)F]FPEB and PET

The metabotropic glutamate receptor 5 (mGluR5) is a promising treatment target for psychiatric disorders due to its modulatory effects on glutamate transmission. Using [(11)C]ABP688, we previously showed that the rapidly acting antidepressant ketamine decreases mGluR5 availability. The mGluR5 radiol...

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Détails bibliographiques
Publié dans:J Cereb Blood Flow Metab
Auteurs principaux: Holmes, Sophie E, Gallezot, Jean-Dominique, Davis, Margaret T, DellaGioia, Nicole, Matuskey, David, Nabulsi, Nabeel, Krystal, John H, Javitch, Jonathan A, DeLorenzo, Christine, Carson, Richard E, Esterlis, Irina
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2019
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585925/
https://ncbi.nlm.nih.gov/pubmed/31744389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X19886316
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