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Exploring the activation pathway and G(i)-coupling specificity of the μ-opioid receptor
Understanding the activation mechanism of the μ-opioid receptor (μ-OR) and its selective coupling to the inhibitory G protein (G(i)) is vital for pharmaceutical research aimed at finding treatments for the opioid overdose crisis. Many attempts have been made to understand the mechanism of the μ-OR a...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7585030/ https://ncbi.nlm.nih.gov/pubmed/33020275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013364117 |
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