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Exploring the Drug Resistance of HCV Protease

Hepatitis C virus (HCV) currently affects several million people across the globe. One of the major classes of drugs against HCV inhibits the NS3/4A protease of the polyprotein chain. Efficacy of these drugs is severely limited due to the high mutation rate that results in several genetically relate...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Jindal, Garima, Mondal, Dibyendu, Warshel, Arieh
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237193/
https://ncbi.nlm.nih.gov/pubmed/28635289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b04562
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