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Role for G protein-coupled receptor kinase in agonist-specific regulation of μ-opioid receptor responsiveness

The G protein-coupled μ-opioid receptor (μOR) mediates the physiological effects of endogenous opioid peptides as well as the structurally distinct opioid alkaloids morphine and etorphine. An intriguing feature of μOR signaling is the differential receptor trafficking and desensitization properties...

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Detalhes bibliográficos
Main Authors: Zhang, Jie, Ferguson, Stephen S. G., Barak, Larry S., Bodduluri, Sobha R., Laporte, Stéphane A., Law, Ping-Yee, Caron, Marc G.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22772/
https://ncbi.nlm.nih.gov/pubmed/9618555
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