Role for G protein-coupled receptor kinase in agonist-specific regulation of μ-opioid receptor responsiveness

The G protein-coupled μ-opioid receptor (μOR) mediates the physiological effects of endogenous opioid peptides as well as the structurally distinct opioid alkaloids morphine and etorphine. An intriguing feature of μOR signaling is the differential receptor trafficking and desensitization properties...

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Hlavní autoři: Zhang, Jie, Ferguson, Stephen S. G., Barak, Larry S., Bodduluri, Sobha R., Laporte, Stéphane A., Law, Ping-Yee, Caron, Marc G.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1998
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC22772/
https://ncbi.nlm.nih.gov/pubmed/9618555
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