Myostatin regulates fatty acid desaturation and fat deposition through MEF2C/miR222/SCD5 cascade in pigs

Myostatin (MSTN), associated with the “double muscling” phenotype, affects muscle growth and fat deposition in animals, whereas how MSTN affects adipogenesis remains to be discovered. Here we show that MSTN can act through the MEF2C/miR222/SCD5 cascade to regulate fatty acid metabolism. We generated...

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發表在:Commun Biol
Main Authors: Ren, Hongyan, Xiao, Wei, Qin, Xingliang, Cai, Gangzhi, Chen, Hao, Hua, Zaidong, Cheng, Cheng, Li, Xinglei, Hua, Wenjun, Xiao, Hongwei, Zhang, Liping, Dai, Jiali, Zheng, Xinmin, Zhu, Zhe, Qian, Chong, Yao, Jie, Bi, Yanzhen
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584575/
https://ncbi.nlm.nih.gov/pubmed/33097765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01348-8
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