Myostatin regulates fatty acid desaturation and fat deposition through MEF2C/miR222/SCD5 cascade in pigs

Myostatin (MSTN), associated with the “double muscling” phenotype, affects muscle growth and fat deposition in animals, whereas how MSTN affects adipogenesis remains to be discovered. Here we show that MSTN can act through the MEF2C/miR222/SCD5 cascade to regulate fatty acid metabolism. We generated...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Ren, Hongyan, Xiao, Wei, Qin, Xingliang, Cai, Gangzhi, Chen, Hao, Hua, Zaidong, Cheng, Cheng, Li, Xinglei, Hua, Wenjun, Xiao, Hongwei, Zhang, Liping, Dai, Jiali, Zheng, Xinmin, Zhu, Zhe, Qian, Chong, Yao, Jie, Bi, Yanzhen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584575/
https://ncbi.nlm.nih.gov/pubmed/33097765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01348-8
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