Myostatin regulates fatty acid desaturation and fat deposition through MEF2C/miR222/SCD5 cascade in pigs

Myostatin (MSTN), associated with the “double muscling” phenotype, affects muscle growth and fat deposition in animals, whereas how MSTN affects adipogenesis remains to be discovered. Here we show that MSTN can act through the MEF2C/miR222/SCD5 cascade to regulate fatty acid metabolism. We generated...

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Gepubliceerd in:Commun Biol
Hoofdauteurs: Ren, Hongyan, Xiao, Wei, Qin, Xingliang, Cai, Gangzhi, Chen, Hao, Hua, Zaidong, Cheng, Cheng, Li, Xinglei, Hua, Wenjun, Xiao, Hongwei, Zhang, Liping, Dai, Jiali, Zheng, Xinmin, Zhu, Zhe, Qian, Chong, Yao, Jie, Bi, Yanzhen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584575/
https://ncbi.nlm.nih.gov/pubmed/33097765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01348-8
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