The Commensal Microbiota Enhances ADP-Triggered Integrin α(IIb)β(3) Activation and von Willebrand Factor-Mediated Platelet Deposition to Type I Collagen

The commensal microbiota is a recognized enhancer of arterial thrombus growth. While several studies have demonstrated the prothrombotic role of the gut microbiota, the molecular mechanisms promoting arterial thrombus growth are still under debate. Here, we demonstrate that germ-free (GF) mice, whic...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Kiouptsi, Klytaimnistra, Jäckel, Sven, Wilms, Eivor, Pontarollo, Giulia, Winterstein, Jana, Karwot, Cornelia, Groß, Kathrin, Jurk, Kerstin, Reinhardt, Christoph
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Brief Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583822/
https://ncbi.nlm.nih.gov/pubmed/32998468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197171
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