The Commensal Microbiota Enhances ADP-Triggered Integrin α(IIb)β(3) Activation and von Willebrand Factor-Mediated Platelet Deposition to Type I Collagen

The commensal microbiota is a recognized enhancer of arterial thrombus growth. While several studies have demonstrated the prothrombotic role of the gut microbiota, the molecular mechanisms promoting arterial thrombus growth are still under debate. Here, we demonstrate that germ-free (GF) mice, whic...

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Foilsithe in:Int J Mol Sci
Main Authors: Kiouptsi, Klytaimnistra, Jäckel, Sven, Wilms, Eivor, Pontarollo, Giulia, Winterstein, Jana, Karwot, Cornelia, Groß, Kathrin, Jurk, Kerstin, Reinhardt, Christoph
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
Ábhair:
Brief Report
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583822/
https://ncbi.nlm.nih.gov/pubmed/32998468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197171
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