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The Commensal Microbiota Enhances ADP-Triggered Integrin α(IIb)β(3) Activation and von Willebrand Factor-Mediated Platelet Deposition to Type I Collagen

The commensal microbiota is a recognized enhancer of arterial thrombus growth. While several studies have demonstrated the prothrombotic role of the gut microbiota, the molecular mechanisms promoting arterial thrombus growth are still under debate. Here, we demonstrate that germ-free (GF) mice, whic...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kiouptsi, Klytaimnistra, Jäckel, Sven, Wilms, Eivor, Pontarollo, Giulia, Winterstein, Jana, Karwot, Cornelia, Groß, Kathrin, Jurk, Kerstin, Reinhardt, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583822/
https://ncbi.nlm.nih.gov/pubmed/32998468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197171
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