The Commensal Microbiota Enhances ADP-Triggered Integrin α(IIb)β(3) Activation and von Willebrand Factor-Mediated Platelet Deposition to Type I Collagen

The commensal microbiota is a recognized enhancer of arterial thrombus growth. While several studies have demonstrated the prothrombotic role of the gut microbiota, the molecular mechanisms promoting arterial thrombus growth are still under debate. Here, we demonstrate that germ-free (GF) mice, whic...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Kiouptsi, Klytaimnistra, Jäckel, Sven, Wilms, Eivor, Pontarollo, Giulia, Winterstein, Jana, Karwot, Cornelia, Groß, Kathrin, Jurk, Kerstin, Reinhardt, Christoph
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583822/
https://ncbi.nlm.nih.gov/pubmed/32998468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197171
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