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Exploiting defects in homologous recombination repair for metastatic, castration-resistant prostate cancer

The PROfound trial highlights that there is a benefit in testing genes involved in homologous recombination (HR) and forms the rationale for testing in all patients with metastatic, castration-resistant prostate cancer (mCRPC). This trial also demostrates that olaparib improves progression free surv...

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Detalles Bibliográficos
Publicado en:Cancer Biol Ther
Main Authors: Chau, Vincent, Madan, Ravi A., Figg, William D.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583699/
https://ncbi.nlm.nih.gov/pubmed/32844710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2020.1809913
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