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Exploiting defects in homologous recombination repair for metastatic, castration-resistant prostate cancer
The PROfound trial highlights that there is a benefit in testing genes involved in homologous recombination (HR) and forms the rationale for testing in all patients with metastatic, castration-resistant prostate cancer (mCRPC). This trial also demostrates that olaparib improves progression free surv...
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| Pubblicato in: | Cancer Biol Ther |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7583699/ https://ncbi.nlm.nih.gov/pubmed/32844710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2020.1809913 |
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