Characterization of Allele-Specific Regulation of Telomerase Reverse Transcriptase in Promoter Mutant Thyroid Cancer Cell Lines

Background: Telomerase reverse transcriptase (TERT) promoter mutations play a role in carcinogenesis and are found in both tumors and cancer cell lines. TERT promoter methylation, transcription factor binding, chromatin remodeling, and alternative splicing are also known to play an integral role in...

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Dettagli Bibliografici
Pubblicato in:Thyroid
Autori principali: McKelvey, Brittany A., Gilpatrick, Timothy, Wang, Yongchun, Timp, Winston, Umbricht, Christopher B., Zeiger, Martha A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc., publishers 2020
Soggetti:
Thyroid Cancer and Nodules
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583328/
https://ncbi.nlm.nih.gov/pubmed/32228178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2020.0055
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