Characterization of Human Telomerase Reverse Transcriptase Promoter Methylation and Transcription Factor Binding in Differentiated Thyroid Cancer Cell Lines

Telomerase reverse transcriptase (TERT) activation plays an important role in cancer development by enabling the immortalization of cells. TERT regulation is multifaceted, and its promoter methylation has been implicated in controlling expression through alteration in transcription factor binding. W...

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Опубликовано в: :Genes Chromosomes Cancer
Главные авторы: Avin, Brittany A., Wang, Yongchun, Gilpatrick, Timothy, Workman, Rachael E., Lee, Isac, Timp, Winston, Umbricht, Christopher B., Zeiger, Martha A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621557/
https://ncbi.nlm.nih.gov/pubmed/30664813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22735
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