Characterization of Allele-Specific Regulation of Telomerase Reverse Transcriptase in Promoter Mutant Thyroid Cancer Cell Lines

Background: Telomerase reverse transcriptase (TERT) promoter mutations play a role in carcinogenesis and are found in both tumors and cancer cell lines. TERT promoter methylation, transcription factor binding, chromatin remodeling, and alternative splicing are also known to play an integral role in...

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Detalles Bibliográficos
Publicado en:Thyroid
Autores principales: McKelvey, Brittany A., Gilpatrick, Timothy, Wang, Yongchun, Timp, Winston, Umbricht, Christopher B., Zeiger, Martha A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Thyroid Cancer and Nodules
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583328/
https://ncbi.nlm.nih.gov/pubmed/32228178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2020.0055
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