Co-encapsulation of HNF4α overexpressing UMSCs and human primary hepatocytes ameliorates mouse acute liver failure

BACKGROUND: Acute liver failure (ALF) is a complicated condition that is characterized by global hepatocyte death and often requires immediate liver transplantation. However, this therapy is limited by shortage of donor organs. Mesenchymal stem cells (MSCs) and hepatocytes are two attractive sources...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Kong, Defu, Xu, Huiming, Chen, Mo, Yu, Yeping, Qian, Yongbing, Qin, Tian, Tong, Ying, Xia, Qiang, Hang, Hualian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583302/
https://ncbi.nlm.nih.gov/pubmed/33097090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01962-7
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