Co-encapsulation of HNF4α overexpressing UMSCs and human primary hepatocytes ameliorates mouse acute liver failure

BACKGROUND: Acute liver failure (ALF) is a complicated condition that is characterized by global hepatocyte death and often requires immediate liver transplantation. However, this therapy is limited by shortage of donor organs. Mesenchymal stem cells (MSCs) and hepatocytes are two attractive sources...

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Publicat a:Stem Cell Res Ther
Autors principals: Kong, Defu, Xu, Huiming, Chen, Mo, Yu, Yeping, Qian, Yongbing, Qin, Tian, Tong, Ying, Xia, Qiang, Hang, Hualian
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583302/
https://ncbi.nlm.nih.gov/pubmed/33097090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01962-7
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