Co-encapsulation of HNF4α overexpressing UMSCs and human primary hepatocytes ameliorates mouse acute liver failure

BACKGROUND: Acute liver failure (ALF) is a complicated condition that is characterized by global hepatocyte death and often requires immediate liver transplantation. However, this therapy is limited by shortage of donor organs. Mesenchymal stem cells (MSCs) and hepatocytes are two attractive sources...

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Veröffentlicht in:Stem Cell Res Ther
Hauptverfasser: Kong, Defu, Xu, Huiming, Chen, Mo, Yu, Yeping, Qian, Yongbing, Qin, Tian, Tong, Ying, Xia, Qiang, Hang, Hualian
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583302/
https://ncbi.nlm.nih.gov/pubmed/33097090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01962-7
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