Changes in the frequencies of Plasmodium falciparum dhps and dhfr drug-resistant mutations in children from Western Kenya from 2005 to 2018: the rise of Pfdhps S436H

BACKGROUND: Sulfadoxine-pyrimethamine (SP) is the only anti-malarial drug formulation approved for intermittent preventive treatment in pregnancy (IPTp). However, mutations in the Plasmodium falciparum dhfr (Pfdhfr) and dhps (Pfdhps) genes confer resistance to pyrimethamine and sulfadoxine, respecti...

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Bibliographic Details
Published in:Malar J
Main Authors: Pacheco, M. Andreína, Schneider, Kristan A., Cheng, Qiuying, Munde, Elly O., Ndege, Caroline, Onyango, Clinton, Raballah, Evans, Anyona, Samuel B., Ouma, Collins, Perkins, Douglas J., Escalante, Ananias A.
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583259/
https://ncbi.nlm.nih.gov/pubmed/33092587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-020-03454-8
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