Differences in selective pressure on dhps and dhfr drug resistant mutations in western Kenya

BACKGROUND: Understanding the origin and spread of mutations associated with drug resistance, especially in the context of combination therapy, will help guide strategies to halt and prevent the emergence of resistance. Unfortunately, studies have assessed these complex processes when resistance is...

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Main Authors: McCollum, Andrea M, Schneider, Kristan A, Griffing, Sean M, Zhou, Zhiyong, Kariuki, Simon, Ter-Kuile, Feiko, Shi, Ya Ping, Slutsker, Laurence, Lal, Altaf A, Udhayakumar, Venkatachalam, Escalante, Ananias A
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338400/
https://ncbi.nlm.nih.gov/pubmed/22439637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-77
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