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Common Origin and Fixation of Plasmodium falciparum dhfr and dhps Mutations Associated with Sulfadoxine-Pyrimethamine Resistance in a Low-Transmission Area in South America

Recent studies indicated that sensitive parasites could increase in frequency in a population when drugs are removed, suggesting that the life span of affordable antimalarial drugs could be expanded. We studied 97 samples from Bolivar State, Venezuela, an area where sulfadoxine-pyrimethamine (SP) ha...

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Bibliografski detalji
Glavni autori: McCollum, Andrea M., Mueller, Kristen, Villegas, Leopoldo, Udhayakumar, Venkatachalam, Escalante, Ananias A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891388/
https://ncbi.nlm.nih.gov/pubmed/17283199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01228-06
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