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Actions of FTY720 (Fingolimod), a Sphingosine-1-Phosphate Receptor Modulator, on Delayed-Rectifier K(+) Current and Intermediate-Conductance Ca(2+)-Activated K(+) Channel in Jurkat T-Lymphocytes

FTY720 (fingolimod), a modulator of sphingosine-1-phosphate receptors, is known to produce the immunomodulatory actions and to be beneficial for treating the relapsing multiple sclerosis. However, whether it exerts any effects on membrane ion currents in immune cells remains largely unknown. Herein,...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Chang, Wei-Ting, Liu, Ping-Yen, Wu, Sheng-Nan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582672/
https://ncbi.nlm.nih.gov/pubmed/33023219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25194525
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