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Actions of FTY720 (Fingolimod), a Sphingosine-1-Phosphate Receptor Modulator, on Delayed-Rectifier K(+) Current and Intermediate-Conductance Ca(2+)-Activated K(+) Channel in Jurkat T-Lymphocytes

FTY720 (fingolimod), a modulator of sphingosine-1-phosphate receptors, is known to produce the immunomodulatory actions and to be beneficial for treating the relapsing multiple sclerosis. However, whether it exerts any effects on membrane ion currents in immune cells remains largely unknown. Herein,...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Chang, Wei-Ting, Liu, Ping-Yen, Wu, Sheng-Nan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582672/
https://ncbi.nlm.nih.gov/pubmed/33023219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25194525
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