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Actions of FTY720 (Fingolimod), a Sphingosine-1-Phosphate Receptor Modulator, on Delayed-Rectifier K(+) Current and Intermediate-Conductance Ca(2+)-Activated K(+) Channel in Jurkat T-Lymphocytes

FTY720 (fingolimod), a modulator of sphingosine-1-phosphate receptors, is known to produce the immunomodulatory actions and to be beneficial for treating the relapsing multiple sclerosis. However, whether it exerts any effects on membrane ion currents in immune cells remains largely unknown. Herein,...

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Bibliografski detalji
Izdano u:Molecules
Glavni autori: Chang, Wei-Ting, Liu, Ping-Yen, Wu, Sheng-Nan
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582672/
https://ncbi.nlm.nih.gov/pubmed/33023219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25194525
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