Epigenetic alterations in skin homing CD4(+)CLA(+) T cells of atopic dermatitis patients

T cells expressing the cutaneous lymphocyte antigen (CLA) mediate pathogenic inflammation in atopic dermatitis (AD). The molecular alterations contributing to their dysregulation remain unclear. With the aim to elucidate putative altered pathways in AD we profiled DNA methylation levels and miRNA ex...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Acevedo, Nathalie, Benfeitas, Rui, Katayama, Shintaro, Bruhn, Sören, Andersson, Anna, Wikberg, Gustav, Lundeberg, Lena, Lindvall, Jessica M., Greco, Dario, Kere, Juha, Söderhäll, Cilla, Scheynius, Annika
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582180/
https://ncbi.nlm.nih.gov/pubmed/33093567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74798-z
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