Protein Tyrosine Phosphatase Receptor S Acts as a Metastatic Suppressor in Malignant Peripheral Nerve Sheath Tumor via Profilin 1-Induced Epithelial-Mesenchymal Transition

Malignant peripheral nerve sheath tumors (MPNST) are aggressive sarcomas with over half of cases developed in the context of neurofibromatosis type 1. Surgical resection is the only effective therapy for MPNST. The prognosis is very dismal once recurrence or metastasis occurs. Epithelial-mesenchymal...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Ren, Jie-Yi, Gu, Yi-Hui, Cui, Xi-Wei, Long, Man-Mei, Wang, Wei, Wei, Cheng-Jiang, Gu, Bin, Zhang, Hai-Bing, Li, Qing-Feng, Wang, Zhi-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581944/
https://ncbi.nlm.nih.gov/pubmed/33163494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.582220
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