Protein Tyrosine Phosphatase Receptor S Acts as a Metastatic Suppressor in Malignant Peripheral Nerve Sheath Tumor via Profilin 1-Induced Epithelial-Mesenchymal Transition

Malignant peripheral nerve sheath tumors (MPNST) are aggressive sarcomas with over half of cases developed in the context of neurofibromatosis type 1. Surgical resection is the only effective therapy for MPNST. The prognosis is very dismal once recurrence or metastasis occurs. Epithelial-mesenchymal...

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Detalles Bibliográficos
Publicado en:Front Cell Dev Biol
Autores principales: Ren, Jie-Yi, Gu, Yi-Hui, Cui, Xi-Wei, Long, Man-Mei, Wang, Wei, Wei, Cheng-Jiang, Gu, Bin, Zhang, Hai-Bing, Li, Qing-Feng, Wang, Zhi-Chao
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581944/
https://ncbi.nlm.nih.gov/pubmed/33163494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.582220
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