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Protein Tyrosine Phosphatase Receptor S Acts as a Metastatic Suppressor in Malignant Peripheral Nerve Sheath Tumor via Profilin 1-Induced Epithelial-Mesenchymal Transition

Malignant peripheral nerve sheath tumors (MPNST) are aggressive sarcomas with over half of cases developed in the context of neurofibromatosis type 1. Surgical resection is the only effective therapy for MPNST. The prognosis is very dismal once recurrence or metastasis occurs. Epithelial-mesenchymal...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Cell Dev Biol
Prif Awduron: Ren, Jie-Yi, Gu, Yi-Hui, Cui, Xi-Wei, Long, Man-Mei, Wang, Wei, Wei, Cheng-Jiang, Gu, Bin, Zhang, Hai-Bing, Li, Qing-Feng, Wang, Zhi-Chao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581944/
https://ncbi.nlm.nih.gov/pubmed/33163494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.582220
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