Selective neuronal vulnerability in Alzheimer’s disease: a network-based analysis

A major obstacle to treating Alzheimer’s disease (AD) is our lack of understanding of the molecular mechanisms underlying selective neuronal vulnerability, which is a key characteristic of the disease. Here we present a framework integrating high-quality neuron type-specific molecular profiles acros...

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Bibliographic Details
Published in:Neuron
Main Authors: Roussarie, Jean-Pierre, Yao, Vicky, Rodriguez-Rodriguez, Patricia, Oughtred, Rose, Rust, Jennifer, Plautz, Zakary, Kasturia, Shirin, Albornoz, Christian, Wang, Wei, Schmidt, Eric F, Dannenfelser, Ruth, Tadych, Alicja, Brichta, Lars, Barnea-Cramer, Alona, Heintz, Nathaniel, Hof, Patrick R., Heiman, Myriam, Dolinski, Kara, Flajolet, Marc, Troyanskaya, Olga G, Greengard, Paul
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7580783/
https://ncbi.nlm.nih.gov/pubmed/32603655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2020.06.010
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