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Regulation of Alzheimer's disease amyloid-β formation by casein kinase I
Alzheimer's disease (AD) is associated with accumulation of the neurotoxic peptide amyloid-β (Aβ), which is produced by sequential cleavage of amyloid precursor protein (APP) by the aspartyl protease β-secretase and the presenilin-dependent protease γ-secretase. An increase of casein kinase 1 (...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1820725/ https://ncbi.nlm.nih.gov/pubmed/17360493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611236104 |
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