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Casein kinase I phosphorylates and destabilizes the β-catenin degradation complex
Wnt signaling plays a key role in cell proliferation and development. Recently, casein kinase I (CKI) and protein phosphatase 2A (PP2A) have emerged as positive and negative regulators of the Wnt pathway, respectively. However, it is not clear how these two enzymes with opposing functions regulate W...
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| Asıl Yazarlar: | , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The National Academy of Sciences
2002
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122164/ https://ncbi.nlm.nih.gov/pubmed/11818547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032468199 |
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