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Wnt-regulated lncRNA discovery enhanced by in vivo identification and CRISPRi functional validation
BACKGROUND: Wnt signaling is an evolutionarily conserved developmental pathway that is frequently hyperactivated in cancer. While multiple protein-coding genes regulated by Wnt signaling are known, the functional lncRNAs regulated by Wnt signaling have not been systematically characterized. METHODS:...
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| Publicado no: | Genome Med |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7580003/ https://ncbi.nlm.nih.gov/pubmed/33092630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-020-00788-5 |
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