Loss of PRCD alters number and packaging density of rhodopsin in rod photoreceptor disc membranes

Progressive rod-cone degeneration (PRCD) is a small protein localized to photoreceptor outer segment (OS) disc membranes. Several mutations in PRCD are linked to retinitis pigmentosa (RP) in canines and humans, and while recent studies have established that PRCD is required for high fidelity disc mo...

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Vydáno v:Sci Rep
Hlavní autoři: Sechrest, Emily R., Murphy, Joseph, Senapati, Subhadip, Goldberg, Andrew F. X., Park, Paul S.-H., Kolandaivelu, Saravanan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577997/
https://ncbi.nlm.nih.gov/pubmed/33087780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74628-2
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