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Palmitoylation of Progressive Rod-Cone Degeneration (PRCD) Regulates Protein Stability and Localization

Progressive rod-cone degeneration (PRCD) is a photoreceptor outer segment (OS) disc-specific protein with unknown function that is associated with retinitis pigmentosa (RP). The most common mutation in PRCD linked with severe RP phenotype is substitution of the only cysteine to tyrosine (C2Y). In th...

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Vydáno v:J Biol Chem
Hlavní autoři: Murphy, Joseph, Kolandaivelu, Saravanan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087724/
https://ncbi.nlm.nih.gov/pubmed/27613864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.742767
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