Linkage Disequilibrium Mapping in Domestic Dog Breeds Narrows the Progressive Rod-Cone Degeneration (prcd) Interval and Identifies Ancestral Disease Transmitting Chromosome

Canine progressive rod-cone degeneration (prcd) is a retinal disease previously mapped to a broad, gene-rich centromeric region of canine chromosome 9. As allelic disorders are present in multiple breeds, we used linkage disequilibrium (LD) to narrow the ∼6.4 Mb interval candidate region. Multiple d...

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Autors principals: Goldstein, Orly, Zangerl, Barbara, Pearce-Kelling, Sue, Sidjanin, Duska J., Kijas, James W., Felix, Jeanette, Acland, Gregory M, Aguirre, Gustavo D.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006154/
https://ncbi.nlm.nih.gov/pubmed/16859891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2006.05.013
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