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Palmitoylation of Progressive Rod-Cone Degeneration (PRCD) Regulates Protein Stability and Localization

Progressive rod-cone degeneration (PRCD) is a photoreceptor outer segment (OS) disc-specific protein with unknown function that is associated with retinitis pigmentosa (RP). The most common mutation in PRCD linked with severe RP phenotype is substitution of the only cysteine to tyrosine (C2Y). In th...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Murphy, Joseph, Kolandaivelu, Saravanan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087724/
https://ncbi.nlm.nih.gov/pubmed/27613864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.742767
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