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Loss of PRCD alters number and packaging density of rhodopsin in rod photoreceptor disc membranes

Progressive rod-cone degeneration (PRCD) is a small protein localized to photoreceptor outer segment (OS) disc membranes. Several mutations in PRCD are linked to retinitis pigmentosa (RP) in canines and humans, and while recent studies have established that PRCD is required for high fidelity disc mo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sechrest, Emily R., Murphy, Joseph, Senapati, Subhadip, Goldberg, Andrew F. X., Park, Paul S.-H., Kolandaivelu, Saravanan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577997/
https://ncbi.nlm.nih.gov/pubmed/33087780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74628-2
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