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A Novel Genetic Model of Constitutively Active Integrin CD11b/CD18
Pharmacological activation of integrin CD11b/CD18 (α(M)β(2), Mac-1, CR3) shows anti-inflammatory benefits in a variety of animal models of human disease, and it is a novel therapeutic strategy. Reasoning that genetic models can provide an orthogonal and direct system for the mechanistic study of CD1...
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| Publicat a: | J Immunol |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7577938/ https://ncbi.nlm.nih.gov/pubmed/32938725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901402 |
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