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Small molecule 2,3-DCPE induces S phase arrest by activating the ATM/ATR-Chk1-Cdc25A signaling pathway in DLD-1 colon cancer cells

In our previous study, it was reported that 2[[3-(2,3-dichlorophenoxy)propyl]amino]ethanol (2,3-DCPE) induces apoptosis and cell cycle arrest. The current study aimed to investigate the molecular mechanism involved in 2,3-DCPE-induced S phase arrest. The results demonstrated that 2,3-DCPE upregulate...

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Bibliografiske detaljer
Udgivet i:Oncol Lett
Main Authors: Bai, Bingjun, Shan, Lina, Wang, Jianhong, Hu, Jinhui, Zheng, Wenqian, Lv, Yiming, Chen, Kangke, Xu, Dengyong, Zhu, Hongbo
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576987/
https://ncbi.nlm.nih.gov/pubmed/33101488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.12157
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