Reduced EGFR and increased miR-221 is associated with increased resistance to temozolomide and radiotherapy in glioblastoma

Despite aggressive treatment with temozolomide and radiotherapy and extensive research into alternative therapies there has been little improvement in Glioblastoma patient survival. Median survival time remains between 12 and 15 months mainly due to treatment resistance and tumor recurrence. In this...

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Pubblicato in:Sci Rep
Autori principali: Areeb, Zammam, Stuart, Sarah F., West, Alice J., Gomez, Juliana, Nguyen, Hong P. T., Paradiso, Lucia, Zulkifli, Ahmad, Jones, Jordan, Kaye, Andrew H., Morokoff, Andrew P., Luwor, Rodney B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576591/
https://ncbi.nlm.nih.gov/pubmed/33082482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74746-x
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