Reduced EGFR and increased miR-221 is associated with increased resistance to temozolomide and radiotherapy in glioblastoma

Despite aggressive treatment with temozolomide and radiotherapy and extensive research into alternative therapies there has been little improvement in Glioblastoma patient survival. Median survival time remains between 12 and 15 months mainly due to treatment resistance and tumor recurrence. In this...

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Publicado no:Sci Rep
Main Authors: Areeb, Zammam, Stuart, Sarah F., West, Alice J., Gomez, Juliana, Nguyen, Hong P. T., Paradiso, Lucia, Zulkifli, Ahmad, Jones, Jordan, Kaye, Andrew H., Morokoff, Andrew P., Luwor, Rodney B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576591/
https://ncbi.nlm.nih.gov/pubmed/33082482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74746-x
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