Inhibition of Radiation and Temozolomide-Induced Invadopodia Activity in Glioma Cells Using FDA-Approved Drugs

The most common primary central nervous system tumor in adults is the glioblastoma multiforme (GBM). The highly invasive nature of GBM cells is a significant factor resulting in the inevitable tumor recurrence and poor patient prognosis. Tumor cells utilize structures known as invadopodia to facilia...

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Bibliographic Details
Published in:Transl Oncol
Main Authors: Whitehead, Clarissa A., Nguyen, Hong P.T., Morokoff, Andrew P., Luwor, Rodney B., Paradiso, Lucia, Kaye, Andrew H., Mantamadiotis, Theo, Stylli, Stanley S.
Format: Artigo
Language:Inglês
Published: Neoplasia Press 2018
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Original article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140414/
https://ncbi.nlm.nih.gov/pubmed/30219696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.08.012
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