EGFRvIII Promotes Cell Survival during Endoplasmic Reticulum Stress through a Reticulocalbin 1-Dependent Mechanism

SIMPLE SUMMARY: A key molecule, EGFRvIII has been shown to provide several growth advantages for brain tumors. However, we have found a new mechanism in which the EGFRvIII provides increased survival to brain cancer cells when under sub-optimal conditions. Specifically, we have found that the EGFRvI...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Gomez, Juliana, Areeb, Zammam, Stuart, Sarah F., Nguyen, Hong P. T., Paradiso, Lucia, Zulkifli, Ahmad, Madan, Sonakshi, Rajagopal, Vijay, Montgomery, Magdalene K., Gan, Hui K., Scott, Andrew M., Jones, Jordan, Kaye, Andrew H., Morokoff, Andrew P., Luwor, Rodney B.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7999088/
https://ncbi.nlm.nih.gov/pubmed/33801941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061198
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