Design and Validation of a Human Brain Endothelial Microvessel-on-a-Chip Open Microfluidic Model Enabling Advanced Optical Imaging

We describe here the design and implementation of an in vitro microvascular open model system using human brain microvascular endothelial cells. The design has several advantages over other traditional closed microfluidic platforms: (1) it enables controlled unidirectional flow of media at physiolog...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Salman, Mootaz M., Marsh, Graham, Kusters, Ilja, Delincé, Matthieu, Di Caprio, Giuseppe, Upadhyayula, Srigokul, de Nola, Giovanni, Hunt, Ronan, Ohashi, Kazuka G., Gray, Taylor, Shimizu, Fumitaka, Sano, Yasuteru, Kanda, Takashi, Obermeier, Birgit, Kirchhausen, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576009/
https://ncbi.nlm.nih.gov/pubmed/33117784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.573775
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