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Downregulation of Keap1 Confers Features of a Fasted Metabolic State
Transcription factor nuclear factor erythroid 2 p45-related factor 2 (Nrf2) and its main negative regulator, Kelch-like ECH-associated protein 1 (Keap1), are at the interface between redox and intermediary metabolism, allowing adaptation and survival under conditions of oxidative, inflammatory, and...
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| Veröffentlicht in: | iScience |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7575887/ https://ncbi.nlm.nih.gov/pubmed/33103077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101638 |
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