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KEAP1, a cysteine-based sensor and a drug target for the prevention and treatment of chronic disease

Redox imbalance and persistent inflammation are the underlying causes of most chronic diseases. Mammalian cells have evolved elaborate mechanisms for restoring redox homeostasis and resolving acute inflammatory responses. One prominent mechanism is that of inducing the expression of antioxidant, ant...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Dayalan Naidu, Sharadha, Dinkova-Kostova, Albena T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333886/
https://ncbi.nlm.nih.gov/pubmed/32574549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200105
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