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KEAP1, a cysteine-based sensor and a drug target for the prevention and treatment of chronic disease

Redox imbalance and persistent inflammation are the underlying causes of most chronic diseases. Mammalian cells have evolved elaborate mechanisms for restoring redox homeostasis and resolving acute inflammatory responses. One prominent mechanism is that of inducing the expression of antioxidant, ant...

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Dades bibliogràfiques
Publicat a:Open Biol
Autors principals: Dayalan Naidu, Sharadha, Dinkova-Kostova, Albena T.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333886/
https://ncbi.nlm.nih.gov/pubmed/32574549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200105
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